Asymptomatic Proteinuria

CLINICAL DIAGNOSTIC MANUAL

Asymptomatic proteinuria refers to the presence of proteins in the urine without evident clinical symptoms. This condition is often detected incidentally during routine examinations.

The presence of proteins in the urine can indicate renal dysfunction or benign and transient conditions. Careful evaluation and identification of the underlying cause are crucial to determining whether the proteinuria is a benign finding or indicative of more serious renal pathology.

Pathology	Clinical Symptoms and Signs	Suspected Diagnosis	Confirmatory Diagnosis
Postural and orthostatic proteinuria	Proteinuria that appears when standing and disappears at rest, no other symptoms	Medical history, urine analysis in supine and standing positions	Fractionated proteinuria test (daytime and nighttime)
Non-specific febrile illness	Fever, general malaise, symptoms of systemic infection, transient proteinuria	Medical history, physical examination, signs of infection	Resolution of proteinuria after recovery
Urinary infection	Dysuria, urinary urgency, suprapubic pain, fever, proteinuria	Medical history, physical examination, signs of infection	Urine culture, urinalysis
Glomerulonephritis	Hematuria, proteinuria, edema, hypertension	Medical history, physical examination, signs of renal insufficiency	Urinalysis, kidney biopsy
Nephritis	Hematuria, proteinuria, edema, hypertension, history of systemic disease	Medical history, physical examination, signs of systemic disease	Urinalysis, kidney biopsy, specific studies for underlying disease
Nephrotic syndrome	Massive proteinuria, edema, hypoalbuminemia, hyperlipidemia	Medical history, physical examination, signs of nephrotic syndrome	Urinalysis, lipid profile, kidney biopsy