Itchy Skin with Hives

CLINICAL DIAGNOSTIC MANUAL

Itchy skin with hives is a common dermatological manifestation characterized by the presence of pruritus (itching) accompanied by raised welts or hives on the skin. This condition can be acute or chronic and may be associated with various causes, including allergic reactions, infections, autoimmune diseases, and hereditary conditions. Identifying the underlying cause is crucial for effective management and treatment.

Pathology	Suspected Diagnosis	Confirmatory Diagnosis
Chronic idiopathic urticaria	Recurrent hives and itching lasting more than 6 weeks, no identifiable cause.	Medical history, physical examination, exclusion of other causes.
Acute urticaria	Sudden onset of hives and itching, usually lasting less than 6 weeks.	Medical history, physical examination, allergy testing.
Physical urticaria	Hives induced by physical stimuli such as cold, heat, pressure, or exercise.	Physical provocation tests, medical history.
Hereditary angioedema	Recurrent episodes of angioedema without itching, family history of the condition.	Genetic testing, levels of C4 and C1 inhibitor.
Linear IgA dermatosis	Vesicular and itchy lesions in linear patterns, primarily in children.	Skin biopsy with direct immunofluorescence, IgA levels.