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Mid-Systolic Murmur

Updated: Sep 19, 2024

CLINICAL DIAGNOSTIC MANUAL



A mid-systolic murmur is an abnormal heart sound heard during the middle phase of systole when the ventricles are contracting and ejecting blood into the main arteries. This type of murmur indicates turbulence in blood flow through the heart valves or major vessels. Identifying and evaluating mid-systolic murmurs is essential for diagnosing various cardiac and vascular pathologies that may have significant clinical implications.

Pathology

Suspected Diagnosis

Confirmatory Diagnosis

Aortic stenosis

Dyspnoea, chest pain, syncope, systolic murmur at the aortic area.

Echocardiogram, ECG, chest X-ray.

Hypertrophic cardiomyopathy

Dyspnoea, palpitations, syncope, systolic murmur that increases with Valsalva.

Echocardiogram, ECG, cardiac MRI (CMR).

Aortic sclerosis

Dyspnoea, fatigue, systolic murmur, aging, aortic valve calcification.

Echocardiogram, chest X-ray, ECG.

High pulmonary flow

Dyspnoea, fatigue, systolic murmur, pulmonary hypertension.

Echocardiogram, pulmonary function tests, chest X-ray.

Atrial septal defect

Dyspnoea, fatigue, systolic murmur at the pulmonary area, cyanosis.

Echocardiogram, ECG, cardiac catheterisation.

Pulmonary stenosis

Dyspnoea, fatigue, systolic murmur at the pulmonary area, cyanosis.

Echocardiogram, ECG, chest X-ray.


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