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Other Causes of Joint and Limb Pain

Updated: Sep 25

MANUAL MINORS



There are various conditions that can cause pain in the joints and limbs, ranging from inflammatory and degenerative diseases to traumatic injuries or infections. Below are some of the most common issues that may cause pain in these areas.


Differential Diagnosis

Condition

Description

Rheumatoid Arthritis

Autoimmune disease causing chronic inflammation in multiple joints, with pain, stiffness, and progressive deformities.

Osteoarthritis

Degenerative wear and tear of joint cartilage, causing mechanical pain, mild morning stiffness, and joint crepitus.

Gout

Acute arthritis caused by the accumulation of urate crystals in joints, commonly affecting the big toe.

Fibromyalgia

Widespread muscle and joint pain, accompanied by fatigue, sleep disturbances, and tenderness in specific points.

Systemic Lupus Erythematosus

Autoimmune disease affecting multiple systems, causing joint pain, skin rashes, and systemic symptoms.

Bursitis

Inflammation of bursae around joints, leading to localised pain, swelling, and tenderness.

Tendinitis

Inflammation of a tendon, causing pain along the affected tendon, especially with muscle movement.

Tenosynovitis

Inflammation of the tendon and its synovial sheath, causing pain and swelling along the tendon and limited movement.

Carpal Tunnel Syndrome

Compression of the median nerve in the wrist, causing pain, numbness, and weakness in the hand and fingers.

Repetitive Strain Injuries (RSI)

Muscle or joint pain caused by repetitive movements, common in jobs requiring continuous motions.

Ankylosing Spondylitis

Chronic inflammatory disease primarily affecting the spine, causing morning pain and stiffness.

Peripheral Neuropathy

Nerve damage causing pain, numbness, tingling, or weakness in the limbs.

Acute Compartment Syndrome

Increased pressure within a muscle compartment causing severe pain, swelling, and risk of tissue damage.

Fractures and Sprains

Traumatic injuries causing sharp pain, swelling, deformity, and functional limitations in the affected bones or joints.

Septic Arthritis (Joint Infection)

Bacterial infection of a joint, causing severe pain, swelling, warmth, and fever.

Emergency Management


Emergency management depends on the cause of the pain. Analgesics and nonsteroidal anti-inflammatory drugs (NSAIDs) are often administered to control pain and inflammation. In cases of infection or suspected septic arthritis, antibiotics should be started immediately. If pain is associated with a fracture or dislocation, immobilisation of the affected area is crucial, and in some cases, reduction of the dislocation is necessary.


Definitive Treatment


Definitive treatment depends on the underlying cause. It often includes physiotherapy, activity modification to prevent joint overload, and in chronic cases, specific medications such as corticosteroids, immunosuppressants, or biologics. Surgical interventions may be required in cases of severe joint damage, such as advanced osteoarthritis or significant traumatic injuries.

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