Vasculitic Nodules on the Fingers

CLINICAL DIAGNOSIS MANUAL

Vasculitic nodules on the fingers are manifestations of inflammation in small blood vessels (capillaries, arterioles, and venules). They can be signs of various systemic diseases and are commonly seen in conditions involving vasculitis or systemic inflammatory processes.

Pathology	Diagnosis of Suspicion	Diagnosis of Confirmation
Systemic Lupus Erythematosus (SLE)	Arthritis symptoms, skin rash, photosensitivity, oral ulcers	Positive ANA and at least 4 of the 11 ACR criteria (anti-nuclear antibodies), which may include specific serology and clinical signs
Subacute Bacterial Endocarditis	Fever, new or changing heart murmur, constitutional symptoms like fatigue and weight loss	Positive blood cultures and echocardiogram showing evidence of vegetations on the heart valves