MANUAL OF CLINICAL DIAGNOSIS
Vomiting accompanied by weight loss is an alarming symptom that may indicate a serious underlying pathology. These symptoms suggest a disruption in the gastrointestinal system that impairs proper digestion and nutrient absorption.
A prompt and thorough evaluation is essential to determine the underlying cause and administer appropriate treatment, as significant weight loss can have severe consequences for the patient’s overall health.
Pathology | Clinical Symptoms and Signs | Suspected Diagnosis | Confirmatory Diagnosis |
Oesophageal Disorders | Dysphagia, chest pain, regurgitation, vomiting, weight loss | Medical history, physical examination | Oesophageal endoscopy, oesophageal manometry, barium swallow |
Oesophageal Carcinoma | Progressive dysphagia, odynophagia, chest pain, vomiting, weight loss, gastrointestinal bleeding | Medical history, physical examination | Endoscopy with biopsy, chest and abdominal computed tomography (CT) |
Gastric Carcinoma | Dyspepsia, nausea, vomiting, early satiety, weight loss, epigastric pain | Medical history, physical examination | Endoscopy with biopsy, abdominal CT, blood tests |
Small Intestine Tumour | Abdominal pain, vomiting, weight loss, gastrointestinal bleeding | Medical history, physical examination | Abdominal CT, capsule endoscopy, enteroscopy |
Achalasia | Dysphagia for solids and liquids, nocturnal regurgitation, chest pain, weight loss | Medical history, physical examination | Oesophageal manometry, barium swallow, endoscopy |
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